IT Sr. Manager, Salesforce Solutions Architect – Commercial Applications

Kiniksa Pharmaceuticals is a commercial‑stage biopharmaceutical company developing and commercializing novel therapies for diseases with unmet need, with a focus on cardiovascular indications. With deep expertise in immunology and inflammation, Kiniksa is advancing a growing portfolio of approved and investigational medicines, anchored by its lead product, ARCALYST®, the first and only FDA‑approved therapy for recurrent pericarditis.

Grounded in rigorous science and bold innovation, the company fosters a highly collaborative, patient‑first culture led by accomplished life sciences leaders. At Kiniksa, talented individuals are trusted and empowered to make a real impact—shaping the future of medicine while improving the lives of patients who need it most. We are seeking a highly skilled and motivated Salesforce Solutions Architect to play a key role in shaping and evolving our Salesforce ecosystem across  commercial, sales, and marketing.

This is a highly visible role with the opportunity to influence how Salesforce capabilities are designed, scaled and used to support a growing organization.   The Salesforce Architect will own solution architecture while remaining hands-on with configuration and delivery, with a focus on Salesforce Service Cloud, Health Cloud, and Marketing Cloud. You will work closely with business leaders and IT partners to translate business needs into practical, scalable solutions that improve user experience, enable new capabilities, and deliver measurable value.

The role is ideal for someone who enjoys operating at the intersection of strategy, technology and execution. Spending approximately 50% of their time designing and building solutions and 50% partnering with business stakeholders and IT peers to ensure scalable, compliant, and high-value Salesforce implementations in a regulated biotech environment. This role is based in our Lexington, MA office and requires employees to be onsite five days per week.

Responsibilities ( including, but not limited to ):   Serve as the technical architect and technical owner for Salesforce Commercial platforms, including Health Cloud, Marketing Cloud and the use of AI features (Agentforce, Einstein, LLMs). Actively design and hands-on configure Salesforce solutions, including objects, flows, security models, data structures, marketing automations and Agentforce AI agents.

Partner closely with Commercial Operations, Marketing, Patient Services and Analytics teams to translate business needs into scalable Salesforce architectures. Design and support Marketing Cloud journeys, integrations, and data synchronization across Salesforce platforms and external systems. Define and enforce Salesforce governance, best practices, and architectural standards across environments and teams.

Design and oversee integrations using APIs and middleware to connect Salesforce with data platforms and third-party vendors. Collaborate with IT Infrastructure, Security, Legal, and Compliance teams to ensure alignment with data privacy and regulatory requirements. Serve as technical liaison to Salesforce and external implementation partners, providing design leadership and quality oversight. Support release management, environment strategy, and deployment across sandboxes and production.

Mentor administrators and developers and promote strong technical practices. Standout Skills for Impact:  Ability to lead brainstorming, requirement and use case sessions with key Business & IT stakeholders. Convert requirements into functional prototypes and convey technical specs to external resources to develop end to end solution. Continually stay abreast of key technology platforms, maintain technical roadmap for next 12 to 18 months.

Present this to Business & IT stakeholders on a set cadence. Qualifications and Experience:   Bachelor’s degree in Computer Science, Information Systems, or related field. 5+ years of Salesforce experience with hands-on co